November 16, 2016

Peptides

Peptide synthesis is most often done using the C-to-N synthesis method. With this method, a carboxyl group of incoming amino acid is coupled to the N-terminus of a growing peptide chain. During the synthesis, the N-terminus of the incoming amino acid is coupled to the C-terminus of the protein chain. Since the nature of in vitro protein synthesis is very complex, the additional amino acids added to the growing peptide